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Protection of rhesus monkeys from fatal Lassa fever by vaccination with a recombinant vaccinia virus containing the Lassa virus glycoprotein gene.

Lassa fever is an acute febrile disease of West Africa, where there are as many as 300,000 infections a year and an estimated 3000 deaths. As control of the rodent host is impracticable at present, the best immediate prospect is vaccination. We tested as potential vaccines in rhesus monkeys a closel...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fisher-Hoch, S P, McCormick, J B, Auperin, D, Brown, B G, Castor, M, Perez, G, Ruo, S, Conaty, A, Brammer, L, Bauer, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911575/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.317
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