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The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer

We describe for the first time the chemopreventive effects of S-(−)equol and R-(+)equol, diastereoisomers with contrasting affinities for estrogen receptors (ERs). S-(−)equol, a ligand for ERβ, is an intestinally derived metabolite formed by many humans and by rodents consuming diets containing soy...

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Hlavní autoři: Brown, Nadine M., Belles, Carrie A., Lindley, Stephanie L., Zimmer-Nechemias, Linda D., Zhao, Xueheng, Witte, David P., Kim, Mi-Ok, Setchell, Kenneth D.R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864409/
https://ncbi.nlm.nih.gov/pubmed/20110282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq025
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