Mapping to molecular resolution in the T to H-2 region of the mouse genome with a nested set of meiotic recombinants.
We describe a meiotic fine-structure mapping strategy for achieving molecular access to developmental mutations in the mouse. The induction of lethal point mutations with the potent germ-line mutagen N-ethyl-N-nitrosourea has been reported. One lethal mutation of prime interest is an allele at the q...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286436/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911572/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.222 |
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