Cytolysis by tumor necrosis factor is preceded by a rapid and specific dissolution of microfilaments.

Tumor necrosis factor (TNF) is cytotoxic to certain transformed cells, whereas normal cells are resistant to its effects. The resistance of normal cells can often be overcome by treatment with inhibitors of transcription or translation such as actinomycin D or cycloheximide (CHI), suggesting that no...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Scanlon, M, Laster, S M, Wood, J G, Gooding, L R
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2643096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.182
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