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Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy

In recent years, tyrosine kinases (TKs) have been recognized as central players and regulators of cancer cell proliferation, apoptosis, and angiogenesis, and are therefore considered suitable potential targets for anti-cancer therapies. Several strategies for targeting TKs have been developed, the m...

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Detalhes bibliográficos
Main Authors: Sierra, J Rafael, Cepero, Virna, Giordano, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864216/
https://ncbi.nlm.nih.gov/pubmed/20385023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-75
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