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Prior Multiple Ethanol Withdrawals Enhance Stress-Induced Anxiety-Like Behavior: Inhibition by CRF(1)- and Benzodiazepine-Receptor Antagonists and a 5-HT(1a)-Receptor Agonist

Repeated withdrawals from chronic ethanol induce a persistent adaptive change. Further, stress substitutes for the initial two withdrawals of a multiple-withdrawal protocol to sensitize rats to withdrawal-induced anxiety-like behavior (‘anxiety’). Therefore, it was tested whether the persistent adap...

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Detalhes bibliográficos
Main Authors: Breese, George R, Overstreet, David H, Knapp, Darin J, Navarro, Montserrat
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864139/
https://ncbi.nlm.nih.gov/pubmed/15726114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1300706
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