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Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine

Replacement of the central isophthalamide core in a synthetic HCl receptor, with a 2,6-dicarboxamidopyridine, leads to a more preorganized molecular structure that exhibits higher chloride affinity and membrane transport flux.

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Detalhes bibliográficos
Main Authors: Gale, Philip A., Garric, Joachim, Light, Mark E., McNally, Beth A., Smith, Bradley D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864111/
https://ncbi.nlm.nih.gov/pubmed/17457425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b703259e
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