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Enzymatic cleavage of a bacterial genome at a 10-base-pair recognition site.

The circular genome of Staphylococcus aureus was cut into two fragments by a simple enzymatic method that cleaves a 10-base-pair site. The recognition sequence, A-T-C-G-mA decreases T-C-G-mA-T, was created by the combined use of the methylase M.Cla I (A-T-C-G-mA-T) and the restriction endonuclease D...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weil, M D, McClelland, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC286401/
https://ncbi.nlm.nih.gov/pubmed/2536159
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