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Automated conformational energy fitting for force-field development

We present a general conformational-energy fitting procedure based on Monte Carlo simulated annealing (MCSA) for application in the development of molecular mechanics force fields. Starting with a target potential energy surface and an unparameterized molecular mechanics potential energy surface, an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guvench, Olgun, MacKerell, Alexander D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864003/
https://ncbi.nlm.nih.gov/pubmed/18458967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-008-0305-0
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