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In the presence of CTP, UTP becomes an allosteric inhibitor of aspartate transcarbamoylase.

The allosteric control of aspartate transcarbamoylase (ATCase, EC 2.1.3.2) of Escherichia coli involves feedback inhibition by both CTP and UTP rather than just CTP alone. It has been known that CTP functions as a heterotropic inhibitor of catalysis; however, the inhibition by CTP alone is incomplet...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wild, J R, Loughrey-Chen, S J, Corder, T S
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286400/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2643106/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.46
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