Acceleration of Hepatitis C Virus Envelope Evolution in Humans Is Consistent with Progressive Humoral Immune Selection during the Transition from Acute to Chronic Infection

During the transition from acute to chronic infection in individuals persistently infected with hepatitis C virus (HCV), cellular responses initiate within the first 6 months of primary infection and collapse thereafter, whereas humoral responses activate later during the chronic phase. Whether and...

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Autors principals: Liu, Lin, Fisher, Brian E., Dowd, Kimberly A., Astemborski, Jacquie, Cox, Andrea L., Ray, Stuart C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Genetic Diversity and Evolution
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863818/
https://ncbi.nlm.nih.gov/pubmed/20200239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02265-09
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