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Induction of Interferon and Interferon Signaling Pathways by Replication of Defective Interfering Particle RNA in Cells Constitutively Expressing Vesicular Stomatitis Virus Replication Proteins

We show here that replication of defective interfering (DI) particle RNA in HEK293 cells stably expressing vesicular stomatitis virus (VSV) replication proteins potently activates interferon (IFN) and IFN signaling pathways through upregulation of IFN-β promoter, IFN-stimulated response element (ISR...

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Detalhes bibliográficos
Main Authors: Panda, Debasis, Dinh, Phat X., Beura, Lalit K., Pattnaik, Asit K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863789/
https://ncbi.nlm.nih.gov/pubmed/20181705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02701-09
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