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Hepatitis B Virus Replication Induces Methylation of both Host and Viral DNA
Control of viral replication is a major therapeutic goal to reduce morbidity and mortality from chronic hepatitis B virus (HBV) infection. Recently, methylation has been identified as a novel host defense mechanism, and methylation of viral DNA leads to downregulation of HBV gene expression. To bett...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863779/ https://ncbi.nlm.nih.gov/pubmed/20147412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02280-09 |
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