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CD317/Tetherin Is Enriched in the HIV-1 Envelope and Downregulated from the Plasma Membrane upon Virus Infection

CD317/Bst-2/tetherin is a host factor that restricts the release of human immunodeficiency virus type 1 (HIV-1) by trapping virions at the plasma membrane of certain producer cells. It is antagonized by the HIV-1 accessory protein Vpu. Previous light microscopy studies localized CD317 to the plasma...

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Autors principals: Habermann, Anja, Krijnse-Locker, Jacomine, Oberwinkler, Heike, Eckhardt, Manon, Homann, Stefanie, Andrew, Amy, Strebel, Klaus, Kräusslich, Hans-Georg
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863769/
https://ncbi.nlm.nih.gov/pubmed/20147389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02421-09
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