Downregulation of Cdc2/CDK1 Kinase Activity Induces the Synthesis of Noninfectious Human Papillomavirus Type 31b Virions in Organotypic Tissues Exposed to Benzo[a]pyrene

Epidemiological studies suggest that human papillomavirus (HPV)-infected women who smoke face an increased risk for developing cervical cancer. We have previously reported that exposure of HPV-positive organotypic cultures to benzo[a]pyrene (BaP), a major carcinogen in cigarette smoke, resulted in e...

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Détails bibliographiques
Auteurs principaux: Alam, Samina, Bowser, Brian S., Conway, Michael J., Israr, Mohd, Ryndock, Eric J., Xi, Long Fu, Meyers, Craig
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Genome Replication and Regulation of Viral Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863740/
https://ncbi.nlm.nih.gov/pubmed/20181698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02431-09
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