Potent Vesicular Stomatitis Virus-Based Avian Influenza Vaccines Provide Long-Term Sterilizing Immunity against Heterologous Challenge

The emergence in 1997 and continuance today of a highly lethal H5N1 avian influenza virus (AIV) causing human disease has raised concern about an impending pandemic and the need for a vaccine to prepare for such an occurrence. We previously generated an efficacious vesicular stomatitis virus (VSV)-b...

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Main Authors: Schwartz, Jennifer A., Buonocore, Linda, Suguitan, Amorsolo L., Silaghi, Alex, Kobasa, Darwyn, Kobinger, Gary, Feldmann, Heinz, Subbarao, Kanta, Rose, John K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863739/
https://ncbi.nlm.nih.gov/pubmed/20181720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02637-09
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