The Gene for Aromatase, a Rate-Limiting Enzyme for Local Estrogen Biosynthesis, Is a Downstream Target Gene of Runx2 in Skeletal Tissues

The essential osteoblast-related transcription factor Runx2 and the female steroid hormone estrogen are known to play pivotal roles in bone homeostasis; however, the functional interaction between Runx2- and estrogen-mediated signaling in skeletal tissues is minimally understood. Here we provide evi...

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Main Authors: Jeong, Jae-Hwan, Jung, Youn-Kwan, Kim, Hyo-Jin, Jin, Jung-Sook, Kim, Hyun-Nam, Kang, Sang-Min, Kim, Shin-Yoon, van Wijnen, Andre J., Stein, Janet L., Lian, Jane B., Stein, Gary S., Kato, Shigeaki, Choi, Je-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863706/
https://ncbi.nlm.nih.gov/pubmed/20231365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00672-09
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