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Characterization of UDP-Glucose Dehydrogenase and UDP-Glucose Pyrophosphorylase Mutants of Proteus mirabilis: Defectiveness in Polymyxin B Resistance, Swarming, and Virulence

Proteus mirabilis is known to be highly resistant to the action of polymyxin B (PB). However, the mechanism underlying PB resistance is not clear. In this study, we used Tn5 transposon mutagenesis to identify genes that may affect PB resistance in P. mirabilis. Two genes, ugd and galU, which may enc...

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Bibliografiske detaljer
Main Authors: Jiang, Sin-Sien, Lin, Tzu-Yi, Wang, Won-Bo, Liu, Ming-Che, Hsueh, Po-Ren, Liaw, Shwu-Jen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863647/
https://ncbi.nlm.nih.gov/pubmed/20160049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01384-09
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