Selection of Known Plasmodium falciparum Resistance-Mediating Polymorphisms by Artemether-Lumefantrine and Amodiaquine- Sulfadoxine-Pyrimethamine but Not Dihydroartemisinin- Piperaquine in Burkina Faso

Artemether-lumefantrine (AL), dihydroartemisinin-piperaquine (DP), and amodiaquine-sulfadoxine-pyrimethamine (AQ-SP) offer excellent antimalarial efficacy but may select for parasite polymorphisms that decrease drug sensitivity. We evaluated the selection of known polymorphisms in genes encoding put...

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Hlavní autoři: Somé, Anyirékun Fabrice, Séré, Yves Y., Dokomajilar, Christian, Zongo, Issaka, Rouamba, Noël, Greenhouse, Bryan, Ouédraogo, Jean-Bosco, Rosenthal, Philip J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863637/
https://ncbi.nlm.nih.gov/pubmed/20231394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01413-09
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