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Many Chromosomal Genes Modulate MarA-Mediated Multidrug Resistance in Escherichia coli
Multidrug resistance (MDR) in clinical isolates of Escherichia coli can be associated with overexpression of marA, a transcription factor that upregulates multidrug efflux and downregulates membrane permeability. Using random transposome mutagenesis, we found that many chromosomal genes and environm...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863627/ https://ncbi.nlm.nih.gov/pubmed/20211899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01420-09 |
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