Peptide Fragments of a β-Defensin Derivative with Potent Bactericidal Activity

β-Defensins are known to be both antimicrobial and able to chemoattract various immune cells. Although the sequences of paralogous genes are not highly conserved, the core defensin structure is retained. Defb14-1C(V) has bactericidal activity similar to that of its parent peptide (murine β-defensin...

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Bibliographic Details
Main Authors: Reynolds, Natalie L., De Cecco, Martin, Taylor, Karen, Stanton, Chloe, Kilanowski, Fiona, Kalapothakis, Jason, Seo, Emily, Uhrin, Dusan, Campopiano, Dominic, Govan, John, Macmillan, Derek, Barran, Perdita, Dorin, Julia R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863616/
https://ncbi.nlm.nih.gov/pubmed/20176896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01568-09
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