MED14 Tethers Mediator to the N-Terminal Domain of Peroxisome Proliferator-Activated Receptor γ and Is Required for Full Transcriptional Activity and Adipogenesis

The Mediator subunit MED1/TRAP220/DRIP205/PBP interacts directly with many nuclear receptors and was long thought to be responsible for tethering Mediator to peroxisome proliferator-activated receptor (PPAR)-responsive promoters. However, it was demonstrated recently that PPARγ can recruit Mediator...

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Bibliographic Details
Main Authors: Grøntved, Lars, Madsen, Maria S., Boergesen, Michael, Roeder, Robert G., Mandrup, Susanne
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863581/
https://ncbi.nlm.nih.gov/pubmed/20194623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01238-09
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