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Control of Adipogenesis by the SUMO-Specific Protease SENP2

Here, we demonstrate that SENP2, a desumoylating enzyme, plays a critical role in the control of adipogenesis. SENP2 expression was markedly increased upon the induction of adipocyte differentiation, and this increase was dependent on protein kinase A activation. Remarkably, knockdown of SENP2 led t...

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Détails bibliographiques
Auteurs principaux: Chung, Sung Soo, Ahn, Byung Yong, Kim, Min, Choi, Hye Hun, Park, Ho Seon, Kang, Shinae, Park, Sang Gyu, Kim, Young-Bum, Cho, Young Min, Lee, Hong Kyu, Chung, Chin Ha, Park, Kyong Soo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863577/
https://ncbi.nlm.nih.gov/pubmed/20194620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00852-09
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