Phosphorylation of MgrA and Its Effect on Expression of the NorA and NorB Efflux Pumps of Staphylococcus aureus

MgrA is a global regulator in Staphylococcus aureus that controls the expression of diverse genes encoding virulence factors and multidrug resistance (MDR) efflux transporters. We identified pknB, which encodes the (Ser/Thr) kinase PknB, in the S. aureus genome. PknB was able to autophosphorylate as...

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Bibliographic Details
Main Authors: Truong-Bolduc, Que Chi, Hooper, David C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Molecular Biology of Pathogens
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863576/
https://ncbi.nlm.nih.gov/pubmed/20233929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00018-10
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