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Putative TetR Family Transcriptional Regulator SCO1712 Encodes an Antibiotic Downregulator in Streptomyces coelicolor

A tetR family transcriptional regulatory gene (SCO1712) was identified as a global antibiotic regulatory gene from a Streptomyces interspecies DNA microarray analysis. SCO1712 disruption in Streptomyces coelicolor not only upregulated antibiotic biosynthesis through pathway-specific regulators when...

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Main Authors: Lee, Han-Na, Huang, Jianqiang, Im, Jong-Hyuk, Kim, Seon-Hye, Noh, Jun-Hee, Cohen, Stanley N., Kim, Eung-Soo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863465/
https://ncbi.nlm.nih.gov/pubmed/20190084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02426-09
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