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The RNA Polymerase-associated Factor 1 Complex (Paf1C) Directly Increases the Elongation Rate of RNA Polymerase I and Is Required for Efficient Regulation of rRNA Synthesis

The rate of ribosome synthesis is proportional to the rate of cell proliferation; thus, transcription of rRNA by RNA polymerase I (Pol I) is an important target for the regulation of this process. Most previous investigations into mechanisms that regulate the rate of ribosome synthesis have focused...

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Bibliografiske detaljer
Main Authors: Zhang, Yinfeng, Smith, Archer D., Renfrow, Matthew B., Schneider, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863250/
https://ncbi.nlm.nih.gov/pubmed/20299458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115220
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