Heparan Sulfate Chain Valency Controls Syndecan-4 Function in Cell Adhesion

Fibroblasts null for the transmembrane proteoglycan, syndecan-4, have an altered actin cytoskeleton, compared with matching wild-type cells. They do not organize α-smooth muscle actin into bundles, but will do so when full-length syndecan-4 is re-expressed. This requires the central V region of the...

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Detalhes bibliográficos
Main Authors: Gopal, Sandeep, Bober, Adam, Whiteford, James R., Multhaupt, Hinke A. B., Yoneda, Atsuko, Couchman, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863221/
https://ncbi.nlm.nih.gov/pubmed/20154082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056945
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