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Probing Adenine Rings and Backbone Linkages Using Base Specific Isotope-Edited Raman Spectroscopy: Application to Group II Intron Ribozyme Domain V

Raman difference spectroscopy is used to probe the properties of a 36-nt RNA molecule, “D5”, which lies at the heart of the catalytic apparatus in group II introns. For D5 that has all its adenine residues labeled with (13)C and (15)N, and utilizing Raman difference spectroscopy, we identify the con...

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書誌詳細
主要な著者: Chen, Yuanyuan, Eldho, Nadukkudy V., Dayie, T. Kwaku, Carey, Paul R.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863103/
https://ncbi.nlm.nih.gov/pubmed/20225830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902117w
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