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Testing NMDA receptor block as a therapeutic strategy for reducing ischaemic damage to CNS white matter

Damage to oligodendrocytes caused by glutamate release contributes to mental or physical handicap in periventricular leukomalacia, spinal cord injury, multiple sclerosis and stroke, and has been attributed to activation of AMPA/kainate receptors. However, glutamate also activates unusual NMDA recept...

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Detalhes bibliográficos
Main Authors: Bakiri, Yamina, Hamilton, Nicola B., Káradóttir, Ragnhildur, Attwell, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863073/
https://ncbi.nlm.nih.gov/pubmed/18046734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20608
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