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The contributions of myelin and axonal caliber to transverse relaxation time in shiverer and neurofilament-deficient mouse models

White matter disorders can involve injury to myelin or axons but the respective contribution of each to clinical course is difficult to evaluate non-invasively. Here, to develop a paradigm for further investigations of axonal pathology by MRI, we compared two genetic mouse models exhibiting relative...

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Autors principals: Dyakin, Victor V., Chen, Yuanxin, Branch, Craig A., Veeranna, Yuan, Aidong, Rao, Mala, Kumar, Asok, Peterhoff, Corrinne M., Nixon, Ralph. A
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862816/
https://ncbi.nlm.nih.gov/pubmed/20226865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2010.03.013
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