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2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases Reactive Oxygen Species Production in Human Endothelial Cells Via Induction of Cytochrome P4501A1

Studies in our laboratory have demonstrated that subchronic 2,3,7,8,-tetrachlorodibenzo-p-dioxin (TCDD) exposure of adult mice results in hypertension, cardiac hypertrophy, and reduced nitric oxide (NO)-mediated vasodilation. Moreover, increased superoxide anion production was observed in cardiovasc...

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Bibliografiske detaljer
Main Authors: Kopf, PG, Walker, MK
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862761/
https://ncbi.nlm.nih.gov/pubmed/20171976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.02.007
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