High Relaxivity Trimetallic Nitride (Gd(3)N) Metallofullerene MRI Contrast Agents with Optimized Functionality

The water soluble poly(ethylene glycol) (PEG) functionalized and hydroxylated endohedral trimetallic nitride metallofullerene derivatives, Gd(3)N@C(80)[DiPEG(OH)(x)], have been synthesized and characterized. The (1)H MRI relaxivities in aqueous solution were measured for the derivatives with four di...

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Detalhes bibliográficos
Main Authors: Zhang, Jianfei, Shu, Chunying, Reid, Jonathan, Owens, Lesley Shantell, Cai, Ting, Gibson, Harry W., Long, Gary L., Corwin, Frank D., Chen, Zhi-Jian, Fatouros, Panos P., Dorn, Harry C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862638/
https://ncbi.nlm.nih.gov/pubmed/20218678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900375n
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