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Simvastatin Inhibits the Activation of p21(ras) and Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson's Disease

Parkinson's disease (PD) is second only to Alzheimer's disease as the most common devastating human neurodegenerative disorder. Despite intense investigation, no interdictive therapy is available for PD. We investigated whether simvastatin, a Food and Drug Administration-approved cholester...

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Bibliografiske detaljer
Main Authors: Ghosh, Anamitra, Roy, Avik, Matras, Joanna, Brahmachari, Saurav, Gendelman, Howard E., Pahan, Kalipada
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862566/
https://ncbi.nlm.nih.gov/pubmed/19864567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4144-09.2009
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