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Oral administration of the anti-proliferative substance taurolidine has no impact on dextran sulfate sodium induced colitis-associated carcinogenesis in mice

BACKGROUND: New chemopreventive strategies for ulcerative colitis (UC)-associated dysplasia and cancer have to be evaluated. Taurolidine (TRD) has anti-inflammatory, anti-proliferative and anti-neoplastic properties with almost absent toxicity. The aim of the study was to determine whether TRD decre...

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Autores principales: Chromik, Ansgar Michael, Huss, Sebastian, Osseili, Hayssam, Daigeler, Adrien, Kersting, Sabine, Sülberg, Dominique, Mittelkötter, Ulrich, Herdegen, Thomas, Uhl, Waldemar, Müller, Annette M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Medknow Publications 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862504/
https://ncbi.nlm.nih.gov/pubmed/20442801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.62536
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