Indirect Inhibition of Toll-like Receptor and Type I Interferon Responses by ITAM-coupled Receptors and Integrins

An important function of immunoreceptor tyrosine-based activation motif (ITAM)-coupled receptors is cross-regulation of heterologous receptor signaling, but mechanisms of cross-inhibition are poorly understood. We show that high avidity ligation of ITAM-coupled β2 integrins and FcγRs in macrophages...

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Autors principals: Wang, Lu, Gordon, Rachael A., Huynh, Linda, Su, Xiaodi, Min, Kyung-Hyun Park, Han, Jiahuai, Arthur, J. Simon, Kalliolias, George D., Ivashkiv, Lionel B.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862476/
https://ncbi.nlm.nih.gov/pubmed/20362473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.03.014
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