A Multiscale Model of Venous Thrombus Formation with Surface-Mediated Control of Blood Coagulation Cascade

A combination of the extended multiscale model, new image processing algorithms, and biological experiments is used for studying the role of Factor VII (FVII) in venous thrombus formation. A detailed submodel of the tissue factor pathway of blood coagulation is introduced within the framework of the...

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Bibliographic Details
Main Authors: Xu, Zhiliang, Lioi, Joshua, Mu, Jian, Kamocka, Malgorzata M., Liu, Xiaomin, Chen, Danny Z., Rosen, Elliot D., Alber, Mark
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Biological Systems and Multicellular Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862154/
https://ncbi.nlm.nih.gov/pubmed/20441735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4331
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