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Glucagon-like Peptide-1 Receptor (GLP-1R) is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway
BACKGROUND: Glucagon-like Peptide-1 (GLP-1) is a naturally occurring peptide secreted by the L-cells of the small intestine. GLP-1 functions as an incretin and stimulates glucose-mediated insulin production by pancreatic β-cells. In this study, we demonstrate that Exendin-4/GLP-1 has a cognate recep...
Bewaard in:
Hoofdauteurs: | , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2010
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862093/ https://ncbi.nlm.nih.gov/pubmed/20225248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23569 |
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