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Glucagon-like Peptide-1 Receptor (GLP-1R) is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

BACKGROUND: Glucagon-like Peptide-1 (GLP-1) is a naturally occurring peptide secreted by the L-cells of the small intestine. GLP-1 functions as an incretin and stimulates glucose-mediated insulin production by pancreatic β-cells. In this study, we demonstrate that Exendin-4/GLP-1 has a cognate recep...

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Bibliografische gegevens
Hoofdauteurs: Gupta, Nitika Arora, Mells, Jamie, Dunham, Richard M., Grakoui, Arash, Handy, Jeffrey, Saxena, Neeraj Kumar, Anania, Frank A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862093/
https://ncbi.nlm.nih.gov/pubmed/20225248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23569
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