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Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation

BACKGROUND: Mercury is a prominent environmental contaminant that causes detrimental effects to human health. Although the liver has been known to be a main target organ, there is limited information on in vivo molecular mechanism of mercury-induced toxicity in the liver. By using transcriptome anal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ung, Choong Yong, Lam, Siew Hong, Hlaing, Mya Myintzu, Winata, Cecilia Lanny, Korzh, Svetlana, Mathavan, Sinnakaruppan, Gong, Zhiyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862047/
https://ncbi.nlm.nih.gov/pubmed/20353558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-212
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