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Dewetting Transitions in Protein Cavities *

In a previous analysis of the solvation of protein active sites, a drying transition was observed in the narrow hydrophobic binding cavity of Cox-2. With the use of a crude metric that often seems able to discriminate those protein cavities that dry from those that do not, we made an extensive searc...

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Autori principali: Young, Tom, Hua, Lan, Huang, Xuhui, Abel, Robert, Friesner, Richard, Berne, B. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861827/
https://ncbi.nlm.nih.gov/pubmed/20225258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22699
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