Lrp4 Regulates Initiation of Ureteric Budding and Is Crucial for Kidney Formation – A Mouse Model for Cenani-Lenz Syndrome

BACKGROUND: Development of the kidney is initiated when the ureteric bud (UB) branches from the Wolffian duct and invades the overlying metanephric mesenchyme (MM) triggering the mesenchymal/epithelial interactions that are the basis of organ formation. Multiple signaling pathways must be integrated...

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Detalhes bibliográficos
Main Authors: Karner, Courtney M., Dietrich, Martin F., Johnson, Eric B., Kappesser, Natalie, Tennert, Christian, Percin, Ferda, Wollnik, Bernd, Carroll, Thomas J., Herz, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861670/
https://ncbi.nlm.nih.gov/pubmed/20454682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010418
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