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Posttranslational Modification of Human Glyoxalase 1 Indicates Redox-Dependent Regulation
BACKGROUND: Glyoxalase 1 (Glo1) and glyoxalase 2 (Glo2) are ubiquitously expressed cytosolic enzymes that catalyze the conversion of toxic α-oxo-aldehydes into the corresponding α-hydroxy acids using L-glutathione (GSH) as a cofactor. Human Glo1 exists in various isoforms; however, the nature of its...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861629/ https://ncbi.nlm.nih.gov/pubmed/20454679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010399 |
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