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Effects of Long-Term Pioglitazone Treatment on Peripheral and Central Markers of Aging
BACKGROUND: Thiazolidinediones (TZDs) activate peroxisome proliferator-activated receptor gamma (PPARγ) and are used clinically to help restore peripheral insulin sensitivity in Type 2 diabetes (T2DM). Interestingly, long-term treatment of mouse models of Alzheimer's disease (AD) with TZDs also...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861595/ https://ncbi.nlm.nih.gov/pubmed/20454453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010405 |
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