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Evidence for STAT4 as a Common Autoimmune Gene: rs7574865 Is Associated with Colonic Crohn's Disease and Early Disease Onset

BACKGROUND: Recent studies demonstrated an association of STAT4 variants with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), indicating that multiple autoimmune diseases share common susceptibility genes. We therefore investigated the influence of STAT4 variants on the susceptibil...

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Detalhes bibliográficos
Main Authors: Glas, Jürgen, Seiderer, Julia, Nagy, Melinda, Fries, Christoph, Beigel, Florian, Weidinger, Maria, Pfennig, Simone, Klein, Wolfram, Epplen, Jörg T., Lohse, Peter, Folwaczny, Matthias, Göke, Burkhard, Ochsenkühn, Thomas, Diegelmann, Julia, Müller-Myhsok, Bertram, Roeske, Darina, Brand, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861592/
https://ncbi.nlm.nih.gov/pubmed/20454450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010373
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