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Reconstructability Analysis as a Tool for Identifying Gene-Gene Interactions in Studies of Human Diseases

There are a number of common human diseases for which the genetic component may include an epistatic interaction of multiple genes. Detecting these interactions with standard statistical tools is difficult because there may be an interaction effect, but minimal or no main effect. Reconstructability...

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Detalhes bibliográficos
Main Authors: Shervais, Stephen, Kramer, Patricia L., Westaway, Shawn K., Cox, Nancy J., Zwick, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Berkeley Electronic Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861311/
https://ncbi.nlm.nih.gov/pubmed/20361857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1516
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