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NS-398, Ibuprofen and COX-2 RNAi produce significantly different gene expression profiles in prostate cancer cells

Cyclooxygenase-2 (COX-2) plays a significant role in tumor development and progression. Nonsteroidal anti-inflammatory drugs (NSAIDs) exhibit potent anticancer effects in vitro and in vivo by COX-2 dependent and independent mechanisms. In this study, we used microarray analysis to identify the chang...

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Bibliografische gegevens
Hoofdauteurs: John-Aryankalayil, Molykutty, Palayoor, Sanjeewani T., Cerna, David, Falduto, Michael T., Magnuson, Scott R., Coleman, C. Norman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861287/
https://ncbi.nlm.nih.gov/pubmed/19139136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0928
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