Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein

In plants and invertebrates, viral-derived siRNAs processed by the RNaseIII Dicer guide Argonaute (AGO) proteins as part of antiviral RNA-induced silencing complexes (RISC). As a counterdefense, viruses produce suppressor proteins (VSRs) that inhibit the host silencing machinery, but their mechanism...

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Autors principals: Azevedo, Jacinthe, Garcia, Damien, Pontier, Dominique, Ohnesorge, Stephanie, Yu, Agnes, Garcia, Shahinez, Braun, Laurence, Bergdoll, Marc, Hakimi, Mohamed Ali, Lagrange, Thierry, Voinnet, Olivier
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
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Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861190/
https://ncbi.nlm.nih.gov/pubmed/20439431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1908710
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