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Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein
In plants and invertebrates, viral-derived siRNAs processed by the RNaseIII Dicer guide Argonaute (AGO) proteins as part of antiviral RNA-induced silencing complexes (RISC). As a counterdefense, viruses produce suppressor proteins (VSRs) that inhibit the host silencing machinery, but their mechanism...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861190/ https://ncbi.nlm.nih.gov/pubmed/20439431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1908710 |
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