Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder

BACKGROUND: Patients with schizophrenia show elevated brain levels of the neuroactive tryptophan metabolite kynurenic acid (KYNA). This astrocyte-derived mediator acts as a neuroprotectant and modulates sensory gating and cognitive function. We measured the levels of KYNA in the cerebrospinal fluid...

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Detalhes bibliográficos
Main Authors: Olsson, Sara K., Samuelsson, Martin, Saetre, Peter, Lindström, Leif, Jönsson, Erik G., Nordin, Conny, Engberg, Göran, Erhardt, Sophie, Landén, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Medical Association 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861136/
https://ncbi.nlm.nih.gov/pubmed/20420770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.090180
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