Flaky Tail Mouse Denotes Human Atopic Dermatitis in the Steady State and by Topical Application with Dermatophagoides pteronyssinus Extract

The barrier abnormality, a loss-of-function mutation in the gene encoding filaggrin (FLG), which is linked to the incidence of atopic dermatitis (AD), is a recently discovered but important factor in the pathogenesis of AD. Flaky tail (Flg(ft)) mice, essentially deficient in filaggrin, have been use...

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Detalhes bibliográficos
Main Authors: Moniaga, Catharina Sagita, Egawa, Gyohei, Kawasaki, Hiroshi, Hara-Chikuma, Mariko, Honda, Tetsuya, Tanizaki, Hideaki, Nakajima, Saeko, Otsuka, Atsushi, Matsuoka, Hiroyuki, Kubo, Akiharu, Sakabe, Jun-ichi, Tokura, Yoshiki, Miyachi, Yoshiki, Amagai, Masayuki, Kabashima, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861103/
https://ncbi.nlm.nih.gov/pubmed/20304960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090957
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