CCR5 Signaling Suppresses Inflammation and Reduces Adverse Remodeling of the Infarcted Heart, Mediating Recruitment of Regulatory T Cells

Myocardial infarction triggers an inflammatory reaction that is involved in cardiac remodeling. Cardiac repair is dependent on regulatory mechanisms that suppress inflammation and prevent excessive matrix degradation. Chemokine induction in the infarcted heart mediates recruitment of leukocyte subse...

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Bibliographic Details
Main Authors: Dobaczewski, Marcin, Xia, Ying, Bujak, Marcin, Gonzalez-Quesada, Carlos, Frangogiannis, Nikolaos G.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861083/
https://ncbi.nlm.nih.gov/pubmed/20382703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090759
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