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Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics

BACKGROUND: Early studies have demonstrated comparable levels of HER2/ErbB2 expression in both breast and ovarian cancer. Trastuzumab (Herceptin), a therapeutic monoclonal antibody directed against HER2, is FDA-approved for the treatment of both early and late stage breast cancer. However, clinical...

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Bibliographic Details
Main Authors: Wilken, Jason A, Webster, Kristy T, Maihle, Nita J
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861058/
https://ncbi.nlm.nih.gov/pubmed/20346177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-3-7
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